Stroke-IMPaCT

This study will investigate the links between the immune system and cognitive decline after stroke. It is looking for people who have not had a stroke to act as ‘control participants’.

Results of this study will be used to inform the development of targeted treatments and improved recovery for people who have a stroke in the future.

The Stroke-Immune Pathways and Cognitive Trajectory (Stroke IMPaCT) study is funded by the Leducq Foundation. It is being carried out by a team of researchers led by Professor Craig Smith at Salford Royal in collaboration with The University of Manchester and Stanford University.

• Healthy volunteers
• Aged 45+
• No previous stroke, brain haemorrhage, brain injury or neurological disorder (eg multiple sclerosis)
• Not taking immunomodulating or immunosuppressant medicines.

• Salford Royal Hospital (part of the Northern Care Alliance)

Taking part will involve one of the following:

Option one
Attending up to three appointments (approx 30 minutes each) where you will be asked to provide basic medical, health and demographic information as well as donating a sample of blood.

Option two
As above with additional assessment of cognitive function and mobility. Following this, you will be invited to attend a brain scan (approx 1 hour).

Participants will be provided with transport or compensated for travel costs. Those selected to undergo a brain scan will receive a payment of £30.

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